Wednesday, 9 September 2026
385 articles · times in UTC
Nature News · 00:00
In the basement of miniaturized relics ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02416-5 Thinking small.
Nature News · 00:00
Ruins of ancient Asian city show engineering prowess and organization ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02821-w The 5,000-year-old city of Liangzhu has mounds, dams and city walls built in a challenging waterlogged site.
Nature News · 00:00
Why we need an International Panel on Inequality ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02806-9 Disparities in income and wealth are growing. A scientific assessment process can give governments the information they need to tackle them.
Nature News · 00:00
Drug-delivering particles aim to breach the blood–brain barrier ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02655-6 The inability to get drugs into the brain has impeded the treatment of cancer and neurodegenerative diseases for decades. Techniques based on nanoparticles and exosomes are vying to provide a solution.
Nature News · 00:00
PLA2G2D in tumour-draining lymph nodes regulates anti-tumour immunity ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10954-1 A specific population of macrophages that express high levels of the enzyme PLA2G2D in tumour-draining lymph nodes is associated with poor prognosis in patients, and inhibiting PLA2G2D improves anti-tumour immunity in mouse models.
Nature News · 00:00
An operational perturbation proteomics-based virtual cell model ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11001-9 Temporal protein-abundance measurements from systematically perturbed breast cancer cell lines were generated to develop ProteinTalks, a virtual cell model that functions as an operational tool for diverse drug discovery tasks.
Nature News · 00:00
Neocortical long-range inhibition promotes cortical synchrony and sleep ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10876-y In mice, a sparse population of sleep-active long-range inhibitory neurons in the neocortex promote widespread cortical synchronization and sleep, revealing a cortical mechanism that contributes to the regulation of sleep.
Nature News · 00:00
Within-family effect of ancestry on complex traits in a Mexican population ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11039-9 This study uses a within-family design to identify significant ancestry differences in complex traits such as height and type 2 diabetes in a genetically diverse population from Mexico City.
Nature News · 00:00
Breaking timescales with generative sampling of conformational transitions ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11025-1 A generative committor-guided path-sampling framework reconstructs rare biomolecular transition pathways and reveals the underlying thermodynamics and kinetics without using predefined collective variables or brute-force sampling, at an ac…
Nature News · 00:00
Phone tutoring boosts math scores when schools are forced to close ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02843-4 Evidence suggests that regular calls can keep kids learning when schooling is disrupted — plus, why a familiar world map may be about to change.
Nature News · 00:00
Highly efficient base editing at PCSK9 and normal human embryo development ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11118-x Highly efficient base editing at PCSK9 and normal human embryo development
Nature News · 00:00
Drug delivery gets subcellular ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02659-2 Therapies that target mitochondria and other organelles are being put to test in the clinic.
Nature News · 00:00
Nasal vaccines could stop pandemics before they begin ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02656-5 Sparking an immune response where microbes enter the body should not only stop a person getting sick, but also prevent them spreading the infection to others.
Nature News · 00:00
Dose once, treat forever: drugs are being engineered to last much longer ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02660-9 Medication that persists inside the body for months or years could transform the treatment and prevention of many conditions — especially in low- and middle-income countries.
Nature News · 00:00
A good drug is useless if it misses its target ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02653-8 The best medicines go exactly where they’re needed in the body— and nowhere else.
Nature News · 00:00
Medicines do no good if people don’t take them ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02658-3 Health psychologist Rob Horne explains why medication non-adherence is such a problem, and how behavioural science can help to address it.
Nature News · 00:00
These six advances could change how drugs are delivered ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02654-7 Medication triggered by your circadian clock, self-assembling delivery systems based on DNA and other highlights from studies and trials.
Nature News · 00:00
Special delivery: bacterial couriers are smuggling drugs into cancers ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02657-4 Microorganisms that deliver treatments to tumours could make chemotherapy, radiotherapy and immunotherapy safer and more effective.
Nature News · 00:00
AI model predicts which breast-cancer drugs work best ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02845-2 Model trained on millions of protein measurements can gauge drug effectiveness in tissue samples taken from people with triple-negative breast cancer.
Nature News · 00:00
Why the super-fun Ig Nobel prizes bring serious value to science ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02793-x Awards that celebrate humour, curiosity and irreverence are a balm in hard times.
Nature News · 00:00
Proximity-guided graph learning reveals tumour-associated proximity antigens ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11003-7 A proximity-mapping atlas defines tumour-associated proximity antigens, revealing disease-associated membrane spatial communities, and identifies EGFR–CDCP1 as a co-target pair that enhances tumour killing by multispecific therapeutics.
Nature News · 00:00
TM184C is a GPCR-like regulator of intercellular exchange and autophagy ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10993-8 TM184C—an ancient G-protein-coupled receptor-like superdark protein involved in regulation of autophagy, intercellular connectivity and material exchange—underscores the promise of exploring the understudied human proteome and beyond.
Nature News · 00:00
Integrated signatures define mutational processes in prostate cancer ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10468-w Eight integrated mutational footprints collectively explain the mutational processes in 85% of primary prostate cancer genomes.
Nature News · 00:00
Anodic Pd membrane H 2 extraction enhances thermochemical dehydrogenation ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11008-2 An electrochemical cell with molten hydroxide and a Pd membrane actively extracts H2 and thereby boosts ammonia and methylcyclohexane conversion, while also delivering purified H2 ready for use.
Nature News · 00:00
Bacteria recruited to treat cancer ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02823-8 Anticancer drugs could be manufactured and delivered by modified microorganisms.
Nature News · 00:00
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10998-3 TRI-611 induces the degradation of ALK fusion proteins via a previously undescribed CRBN recruitment motif, and its preclinical anti-tumour activity highlights TRI-611 as a potential new way of treating ALK-positive non-small-cell lung can…
Nature News · 00:00
How AI is changing PhD programmes: join our free webinar ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02751-7 Learn how artificial intelligence can hone your research skills as well as the potential pitfalls of relying too heavily on it.
Nature News · 00:00
The Einstein test: what happens when AI tries to rediscover relativity? ↗Nature, Published online: 09 September 2026; doi:10.1038/d41586-026-02804-x Scientists are probing whether language models trained on historical data can reproduce creative breakthroughs.
Nature News · 00:00
Imaging cellular activity across all organs reveals body-wide circuits ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10979-6 An imaging system developed to record cellular activity throughout the whole body of zebrafish captures cellular organ dynamics and identifies multiple distributed circuits.
Nature News · 00:00
Predicting genome-wide functional constraints with GPN-Star ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11005-5 GPN-Star, a genomic language model with a phylogeny-aware architecture for whole-genome alignment data, is shown to be a scalable and flexible tool for genetic variant effect prediction across species.
Nature News · 00:00
Ancient proteins identify various Denisovan remains from Southwest China ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10976-9 Identification and proteomic analysis of bone fragments and teeth from an excavation in Southwest China provide insight into the evolution and phenotype of Denisovans and fill a geographical gap in their documented distribution.
Nature News · 00:00
Mobile education builds resilience during shocks in five countries ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10990-x Remote phone-based targeted tutoring in five countries produced large, cost-effective learning gains during school closures, outperforming text messaging and working effectively when delivered by governments or non-governmental organizatio…
Nature News · 00:00
A serpin–myeloid axis in pancreatic cancer heterogeneity and immune evasion ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11002-8 SERPINE1 and SERPINB2-driven fibrin-rich niches locally programme immunosuppressive macrophages and exclude T cells, enabling spatially organized immune evasion in pancreatic ductal carcinoma.
Nature News · 00:00
Denisovans from southwestern China and their subsistence strategies ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10997-4 Evidence from Bianfu Cave shows specialized hunting, expedient stone-tool production and extensive bone use of Denisovans, providing new insights into their ecology, behaviour and cultural legacy in eastern Asia.
Nature News · 00:00
Advancing conflict research and response through satellite-derived data ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-11004-6 Integrating satellite-derived war-damage data with text-based fatality records through improvement, enrichment and fusion mitigates limitations inherent in each source, revealing complex violence dynamics beyond fatality-centric paradigms,…
Nature News · 00:00
Foaming photopolymers as a high-resolution biomimetic printing platform ↗Nature, Published online: 09 September 2026; doi:10.1038/s41586-026-10968-9 Deep-foam photolithography uses light-controlled polymer foaming to create high-resolution, multifunctional microstructures with tunable optical, wetting and fluid-handling properties for advanced manufacturing applications.